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Increased intron retention is linked to Alzheimer’s disease

更新时间:2023-05-28

【摘要】Intron retention in aging and Alzheimer’s disease(AD): AD is an age-related neurodegenerative disorder with pathological accumulation of amyloid plaque(Masters et al., 2015), which can be classified into familial and sporadic form. In familial AD, mutations in genes encoding either amyloid precursor protein or presenilin(PS1 and PS2) cause

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