Pluripotent stem cell derived inhibitory interneurons–principles and applications in health and disease

更新时间:2023-05-28

《Neural Regeneration Research》2020年02期

【摘要】Inhibitory interneurons are gamma-aminobutyric acid-ergic(GABAergic)nerve cells that act to maintain the appropriate excitation-inhibition balance, and synchronise the output of principle cells to generate rhythmic patterns of firing(Kessaris et al., 2014). This critical role, along with their brain-wide distribution, has led to the implication of interneurons in many neuropathologies, including schizophrenia, autism, dystonia and epilepsies

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Pluripotent stem cell derived inhibitory interneurons–principles and applications in health and disease

更新时间:2023-05-28

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